TRIGGER aims to enhance understanding of the links between climate change, human health, and ecosystems for societal advancement. The project involves a diverse consortium of 22 partners from 15 countries with expertise in health, climate science, data management, policy-making, and more. It will establish 5 Climate-Health Connection Labs in European cities for data collection and engagement with citizens, practitioners, and policymakers. The TRIGGER consortium emphasizes Open Science and co-creation for innovation in all project activities.